Welcome to episode 499 of The Whole View! This week, Stacy and Dr. Sarah break down the science behind the determinants of health to find what components contribute to it and what we can do to improve health and wellness for all.
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- Next week is Dr. Sarah’s last week on the podcast! If you missed last week’s announcement, we discussed it there. In next week’s show, we’ll talk more about what’s next for Dr. Sarah, Stacy, and the podcast. Yes, The Whole View is continuing and will still be awesome. Yes, Dr. Sarah will be back as a guest co-host from time to time!
- Human geneticists have studied how variations in genes contribute to variations in disease risk for more than 100 years. A single gene mutation causes some diseases. But, genetic disorders are rare. Diseases not caused by a specific gene mutation, a collection of gene variants increase your risk.
- “Runs in the family” might not be from genetics, but rather from common exposures (e.g., pesticides, contaminated drinking water) due to the shared environment, learned behaviors (lifestyle, diet, smoking, drinking), social determinants of health, and epigenetics might contribute to this phenomenon! Research continues to untangle the genetic contribution.
- Epigenetics identifies genes whose variations are associated with a disease is just the first step in linking genetics and health. Understanding the mechanisms by which the gene is expressed and how it is influenced by other genes, proteins, and the environment is becoming increasingly important.
- Social determinants of health (SDOH) are environmental conditions that affect a wide range of health, functioning, and quality-of-life outcomes and risks. While biological and health behavior accounts for roughly 25% of a population’s health, the other 75% is determined by social determinants.
- Economic stability, education access and quality, health care access and quality, neighborhood and built environment, and social and community context all play into social determinants of health.
- Racism (not race) is a primary driver of social determinants and the inequities in housing, income, and education, especially among communities of color. In many ways, it’s not just one of the social determinants — it’s an underlying structural determinant setting the stage for all other social determinants.
- We encourage our listeners to learn more about social determinants of health, including the links to structural racism.
- And, of course, our day-to-day choices are important too! Briefly – these are important because they impact nutritional status, hormone regulation, metabolic health, gut microbiome health, and immune health.
- Pulling it all together, make sure you focus on what’s in your power to control, advocate for yourself and others, and think of generational change you can implement in your everyday life!
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Recommended Reading & Listening
- The Science Behind Body Image
- The Harm of Weight Discrimination and Stigma – Part 1
- The Harm of Weight Discrimination and Stigma – Part 2
- Banning Sneaky Toxins in Beauty Products – The Paleo Mom
- Safer Cleaning Products – The Paleo Mom
- A Healthier Visit With Aunt Flo – The Paleo Mom
- Mrs. Toth Goes to Washington – The Paleo Mom
- Personal Care Toxins – The Paleo Mom
- Is there real science on Pesticides and the Dirty Dozen? – The Paleo Mom
- Got Water? – The Paleo Mom
- How to Detox Chlorine
- A Conversation around Current Events – The Paleo Mom
- Racial Disparities in Health and Black Lives Matter – The Paleo Mom
- Setting Priorities and Creating Habits During Stressful Times – The Paleo Mom
- Making Time for Self Care Without the Guilt – The Paleo Mom
Sources & References
- Genetics and Health – Genes, Behavior, and the Social Environment – NCBI Bookshelf
- Monogenic autoinflammatory diseases | Rheumatology | Oxford Academic
- Painter et al., 2008
- Lumey et al., 2011; Veenendaal et al., 2013
- Heijmans et al., 2008
- Schulz, 2010
- Kaati et al., 2002
- Bygren et al., 2001
- Vaage et al., 2011
- Kellermann, 2013
- Epigenetic inheritance and the missing heritability
- Frontiers | Epigenetic Inheritance: Concepts, Mechanisms, and Perspectives | Molecular Neuroscience
- (Mathers et al., 2010),
- Christensen and Marsit, 2011
- Talikka et al., 2012
- Cabib and Puglisi-Allegra, 2012
- van Otterdijk et al., 2013
- Jung and Pfeifer, 2015
- Social Determinants of Health – Healthy People 2030 | health.gov/
- Racism as a Determinant of Health: A Systematic Review and Meta-Analysis
- Impact of Race/Ethnicity and Social Determinants of Health on Diabetes Outcomes
- Social Determinants and Differences in Mortality by Race/Ethnicity | Health Disparities | JAMA Network Open | JAMA Network
- Social Determinants of Health Literature Summaries – Healthy People 2030 | health.gov
- Advocates Can Play Important Role in Addressing the Social Determinants of Health for Children – Center For Children and Families
- Social Determinants of Health | Advocacy
- Advocacy for Health Equity
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